Registered Nurse Salary in St. Louis, MO: $86,187 (2024)

The median registered nurse salary in St. Louis, MO is $86,187 per year ($41.44/hour) as of 2026. This is based on official U.S. Bureau of Labor Statistics data. Salaries range from $57,325 for entry-level positions to $124,936 for experienced professionals in the top 10%.

Entry-level registered nurses in St. Louis, MO typically start at around $57,325 per year ($27.56/hour), representing the 10th percentile. New graduates and those with less than 2 years of experience fall into this range. With experience and skill development, salaries can progress to the median of $86,187 within 3-5 years.

Registered Nurses in St. Louis, MO earn a median hourly wage of $41.44 per hour. Hourly rates range from $27.56/hour at entry-level (10th percentile) to $60.07/hour for top earners (90th percentile). Based on a standard 2,080-hour work year, this translates to annual salaries between $57,325 and $124,936.

The median registered nurse salary of $86,187 in St. Louis, MO is slightly below the national median of $93,600 (7.9% lower). The cost of living is also 9% below average. This salary places you at the 50th percentile, meaning half of registered nurses in the area earn more and half earn less.

Registered Nurses in St. Louis, MO earn slightly below the national average. The local median salary of $86,187 is 7.9% lower than the national median of $93,600. The cost of living is also 9% below average. When adjusted for cost of living, the effective salary is approximately $95,129.

The top 10% of registered nurses in St. Louis, MO earn $124,936 or more per year ($60.07/hour). These top earners typically have 10+ years of experience, advanced certifications, specialized expertise, or hold senior/management positions. The 75th percentile earns $103,098, which is a realistic goal for mid-career professionals.

Key skills that can boost registered nurse salary in St. Louis, MO include: Clinical assessment and critical thinking skills, Strong communication and interpersonal abilities, Compassion and emotional resilience, Attention to detail and organizational skills. Professionals with these skills often earn above the median of $86,187, potentially reaching the 75th percentile ($103,098) or higher. Nursing specialty (ICU, emergency, oncology tend to pay more)

St. Louis, MO has a healthy job market for registered nurses, with approximately 3,005 professionals employed in the area. The median salary of $86,187 is slightly below the national average. The cost of living is also 9% below average. Job seekers should consider both salary and local industry demand when evaluating opportunities.

Compare your registered nurse salary to these St. Louis, MO benchmarks: 10th percentile (entry-level): $57,325, 25th percentile: $68,840, 50th percentile (median): $86,187, 75th percentile: $103,098, 90th percentile (top earners): $124,936. If you earn more than $86,187, you're above average for the area.

Beyond the $86,187 median base salary, registered nurses in St. Louis, MO typically receive comprehensive benefits including health insurance (medical, dental, vision), retirement plans (401k with employer matching), paid time off (15-25 days), and potentially bonuses or profit-sharing. Total compensation including benefits typically adds 25-40% to base salary value.

Experienced registered nurses with 5-10 years in St. Louis, MO typically earn $103,098 (75th percentile) to $124,936 (90th percentile) per year. Senior professionals with 10+ years, certifications, or management roles can reach the top 10% at $124,936. Mid-career professionals (3-5 years) usually earn around the median of $86,187.

Registered Nurses in St. Louis, MO can see significant salary growth over their careers. Entry-level ($57,325) to median ($86,187) typically takes 3-5 years. Reaching the 90th percentile ($124,936) may take 10+ years and often requires specialized skills, certifications, or leadership experience. That's a potential growth of $67,611 over a career.